South San Francisco, Calif. - May 14, 2009 - Solazyme, Inc., the renewable oil production company that creates sustainable fuels, industrial chemicals, and health and wellness ingredients from microalgae, today announced that it has received the prestigious TiE50 cleantech award. The award recognizes the top technology start-ups across five vertical categories.

Nearly 1,200 nominated companies were screened and judged by 40 prominent entrepreneurs, venture capitalists, corporate executives and domain experts, following a public polling process that generated more than 50,000 votes. Nominated companies were judged based on their innovation, ingenuity and management excellence.

"We are honored to receive this award from the world's largest entrepreneur organization. TiE really celebrates the spirit of innovation which is what we strive for everyday at Solazyme. Public recognition of the work we do among countless worthy peers is a special honor. Solazyme is thankful to all that follow and support our company." said Jonathan Wolfson, CEO of Solazyme.

Founded in 2003, Solazyme has developed a unique method for the renewable production of oil derived from microalgae. Solazyme's algal oil is used to create high performance biofuels, "green" chemicals and health and wellness ingredients.

TiE is a global organization dedicated to fostering entrepreneurs across its international network. TiE is spread across 53 chapters in 12 countries comprising of 1,800 entrepreneurs and business executives as charter members, and 12,000 aspiring entrepreneurs and professionals as members.

On May 15 and 16, Solazyme will accept the award and deliver a presentation at the TiEcon 2009 conference in Santa Clara, CA.

To learn more about Solazyme, please visit: http://www.solazyme.com.

For more information on TiEcon 2009, please visit: http://tiecon.org/ TiEcon is TiE's premier annual event and is the largest convention in the world dedicated to entrepreneurs. TiE is a global, not-for-profit, non-political, and non-religious organization dedicated to fostering entrepreneurs across its international network. Since its founding in 1992, TiE has grown to become the world's largest organization for entrepreneurs and professionals, with membership spread across 48 chapters in 11 countries. Membership includes over 1,600 experienced entrepreneurs and business executives as Charter Members, and over 10,000

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About Solazyme:

Solazyme, Inc. is a renewable oil production company and the leader in algal synthetic biology. Solazyme’s unique microbial conversion technology process allows algae to produce oil in standard industrial facilities quickly, efficiently and at large scale. These oils are tailored not only for advanced biofuel production, but also as replacements for fossil petroleum and plant oils in a diverse range of products running from green household cleaning supplies to cosmetics and foods. The company was founded in 2003 and has its headquarters in South San Francisco, Calif. For more information, please visit our website: http://www.solazyme.com.

For more inforamtion contact:

Genet Garamendi, Solazyme Inc., 650-963-5228, ggaramendi@solazyme.com

Beth Starkin, Peppercom, 212-931-6108, bstarkin@peppercom.com